Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells
US9333256B2 · kind B2 · utility
18Cited by
5References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 20, 2014 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Aug 20, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods useful for promoting or reducing T-cell trafficking to a target tissue. Also provided are compositions and methods useful for promoting or inhibiting antigen-presenting cell (APC) activation. The invention is related to discovery of functional characteristics of TIM-3, a molecule that is preferentially expressed on the surface of Th1 cells. The methods are useful for treating disorders including cancer, infectious disease, allergy, asthma, and autoimmune disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.