Azido nucleosides and nucleotide analogs
US9346848B2 · kind B2 · utility
11Cited by
10References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 3, 2014 |
| Grant date | May 24, 2016 |
| Priority date | — |
| Expiry date | Nov 3, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are 4′-azido-substituted nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of 4′-azido-substituted nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a 4′-azido-substituted nucleoside, a nucleotide and/or an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.