Bicyclic dihydroquinoline-2-one derivatives
US9353081B2 · kind B2 · utility
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21Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 14, 2012 |
| Grant date | May 31, 2016 |
| Priority date | — |
| Expiry date | Feb 4, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel compounds having the general formula (I)wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 A3 and n are as described herein, compositions including the compounds and methods of using the compounds.The compounds of the present invention are useful as inhibitors of aldosterone synthase. The compounds may be used, for example, in the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.