Patent · US Active

Hydroxylated and methoxylated pyrimidyl cyclopentanes as Akt protein kinase inhibitors

US9359340B2 · kind B2 · utility

9Cited by
36References
101Claims
0Family size

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Key dates

Filing dateAug 12, 2014
Grant dateJun 7, 2016
Priority date
Expiry dateAug 12, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I:Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.