Chamber free nanoreactor system
US9399217B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 27, 2012 |
| Grant date | Jul 26, 2016 |
| Priority date | — |
| Expiry date | May 27, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2001/4038
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Aspects of the invention include methods for improving the accuracy and read length of sequencing reactions by utilizing unlabeled unincorporable nucleotides, or by rephasing colony based sequencing reactions. Other aspects include systems and devices for improved measurement of biological reactions associated with bead which may be removed, utilizing current measurement methods through the counter ions associated with said beads due to the presence of reactants bound or associated with said bead, wherein electrodes for generating and measuring said current may be within the Debye length of said bead. Other aspects of the invention include methods for determining concentrations of input samples, means for reuse of an array, methods and apparatus for separating beads with different charge levels from each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.