Pyridine-2-amides useful as CB2 agonists

US9409866B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Uwe Grether · Weil am Rhein, DE
• Atsushi Kimbara · Tokyo, JP
• Matthias Nettekoven · Weil am Rhein, DE
• Fabienne Ricklin · Hombourg, FR
• Stephan Roever · Inzlingen, DE
• Mark Rogers-Evans · Bottmingen, CH
• Didier Rombach · Mulhouse, FR
• Tanja Schulz-Gasch · Ziefen, CH
• Matthias Valentin Westphal · Zürich, CH

Key dates

• Filing date: Dec 4, 2013
• Grant date: Aug 9, 2016
• Expiry date: Dec 4, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/107
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 agonist and can be used as an active ingredient in a medicament.