5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
US9416154B2 · kind B2 · utility
2Cited by
25References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 10, 2012 |
| Grant date | Aug 16, 2016 |
| Priority date | — |
| Expiry date | Feb 15, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 5′-Substituted Nucleoside Derivatives of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein X, Y, Z, R1, R2 and R3 are as defined herein and B is a 7-deaza-9-purinyl moiety. The present invention also relates to compositions comprising at least one 5′-Substituted Nucleoside Derivative, and methods of using the 5′-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.