Enhanced protein purification through a modified protein A elution
US9428548B2 · kind B2 · utility
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19References
73Claims
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Key dates
| Filing date | Sep 1, 2010 |
| Grant date | Aug 30, 2016 |
| Priority date | — |
| Expiry date | Mar 1, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.