Compounds inhibiting leucine-rich repeat kinase enzyme activity
US9440952B2 · kind B2 · utility
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2References
19Claims
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Key dates
| Filing date | Feb 27, 2014 |
| Grant date | Sep 13, 2016 |
| Priority date | — |
| Expiry date | Feb 27, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.