Patent · US Active

Compositions and methods for inhibiting expression of factor V

US9441225B2 · kind B2 · utility

1Cited by
4References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 14, 2014
Grant dateSep 13, 2016
Priority date
Expiry dateJan 14, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2320/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of Factor V, comprising an antisense strand having a nucleotide sequence which is less that 25 nucleotides in length and which is substantially complementary to at least a part of Factor V. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of Factor V using the pharmaceutical composition; and methods for inhibiting the expression of Factor V in a cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.