BTK inhibitors

US9446130B2 · kind B2 · utility

Assignee

• Merck Sharp & Dohme LLC · US

Inventors

• Ronald Kim · Essen, DE
• Jian Liu · Xi'an, CN
• Hao Wu · Shanghai, CN
• Shilan Liu · Shanghai, CN
• Chundao Yang · Shanghai, CN
• Shuling Zheng · Shanghai, CN

Key dates

• Filing date: Jan 17, 2014
• Grant date: Sep 20, 2016
• Expiry date: Jan 17, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof. Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.