Lightguides to simplify total emission detection for multiphoton microscopy
US9448158B2 · kind B2 · utility
1Cited by
8References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 3, 2012 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Jun 2, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B21/26
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Light collectors for fluorescence microscopy include slab light guides having a specimen volume such as a specimen well configured to retain a specimen. The specimen volume is bounded by a surface of the slab light guide that permits laterally propagating fluorescence to enter the slab light guide and propagate toward a detection or imaging system. Typically, the slab light guide has an elliptical perimeter and the sample volume is situated at a first focus of the elliptical perimeter. A reflector such as a conical reflector is situated at the second focus so as to direct the collected fluorescence to exit the slab light guide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.