Patent · US Active

Benzimidazole derivatives as bromodomain inhibitors

US9458145B2 · kind B2 · utility

11Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 8, 2014
Grant dateOct 4, 2016
Priority date
Expiry dateMay 8, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I)wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, and R5 are described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.