Peptide-based inhibitor of interleukin-10 or interferon-gamma signaling

US9475839B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Nadya I. Tarasova · Frederick, US
• Giorgio Trinchieri · Lansdowne, US
• Howard A. Young · Gaithersburg, US
• C. Andrew Stewart · Frederick, US
• Marco A. Cardone · Frederick, US
• Alan O. Perantoni · Fairfield, US

Key dates

• Filing date: May 11, 2011
• Grant date: Oct 25, 2016
• Expiry date: Dec 30, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/7156
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A peptide or peptidomimetic comprising an amino acid sequence based on conserved regions of IL10 or IFN-gamma receptor sequences, and related compounds and compositions, as well as methods for the use thereof to inhibit cytokine signaling.