Pyrrolidine derived beta 3 adrenergic receptor agonists

US9486448B2 · kind B2 · utility

Assignee

• Merck Sharp & Dohme LLC · US

Inventors

• Kenneth J. Barr · San Francisco, US
• Mark E. Scott · Fairfield, US
• Christopher F. Thompson · Arlington, US
• Neville J. Anthony · Hatfield, US
• Carolyn Michele Cammarano · Newton, US
• Raman K. Bakshi · Edison, US
• Subhendu Kumar Mohanty · Bengaluru, IN
• Chandra Sekhar Korapala · Bengaluru, IN
• Prashant R. Latthe · Bengaluru, IN
• Vyjayanthi N. Kambam · Bengaluru, IN
• Sujit Kumar Sarkar · Bengaluru, IN
• Jayanth Thiruvellore Thatai · Bengaluru, IN

Key dates

• Filing date: Sep 29, 2014
• Grant date: Nov 8, 2016
• Expiry date: Sep 29, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.