Patent · US Active

Method for reduction of 1->2 reading frame shifts

US9487576B2 · kind B2 · utility

0Cited by

3References

3Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Adelbert Grossmann · Murnau am Staffelsee, DE
Friederike Hesse · Munich, DE
Erhard Kopetzki · Penzberg, DE
Wilma Lau · Munich, DE
Christian Schantz · Penzberg, DE

Key dates

Filing date	Aug 29, 2014
Grant date	Nov 8, 2016
Priority date	—
Expiry date	Aug 29, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/67
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Herein is reported a method for the recombinant production of a polypeptide, which comprises the dipeptide AR, characterized in that the method comprises the recovering of the polypeptide from the cells or the cultivation medium of a cultivation of a cell comprising a nucleic acid encoding the polypeptide and thereby producing the polypeptide, whereby the dipeptide AR comprised in the polypeptide is encoded by the oligonucleotide gca cgt, or the oligonucleotide gcg cgt, or the oligonucleotide gcc cgt.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.