Patent · US Active

Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens

US9493578B2 · kind B2 · utility

23Cited by

117References

10Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Gregory Moore · Monrovia, US

Key dates

Filing date	Sep 2, 2010
Grant date	Nov 15, 2016
Priority date	—
Expiry date	Feb 21, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Immunoglobulin compositions that simultaneously co-engage antigens, where one of the antigens is bound bivalently and the other antigen is bound monovalently. The novel immunoglobulins described preferably utilize heterodimeric Fc regions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.