Cancer-related extracellular matrix signatures and related methods and products
US9526800B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 14, 2013 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Mar 14, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with various aspects of cancer. Panels or signature sets of proteins useful in the detection, diagnosis and treatment of cancers as well as monitoring therapeutic progress in a cancer patient are provided herein along with methods for their detection and for their use in targeting imaging and/or therapeutic agents to the tumors via binding to the specified proteins. The proteins were identified using proteomics analyzes of tissue samples taken from cancer patients. In certain aspects the proteins are particularly useful in colon cancer patients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.