Patent · US Active

FXR (NR1H4) binding and activity modulating compounds

US9539244B2 · kind B2 · utility

27Cited by

5References

17Claims

0Family size

Assignee

Gilead Sciences, Inc. · US

Inventors

Olaf Kinzel · Heidelberg, DE
Christoph Steeneck · Dossenheim, DE
Claus Kremoser · Heidelberg, DE

Key dates

Filing date	Aug 12, 2015
Grant date	Jan 10, 2017
Priority date	—
Expiry date	Aug 12, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.