Substituted spirocycles

US9540373B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Viktor Vintonyak · Warthausen, DE
• Matthias Grauert · Ingelheim am Rhein, DE
• Marc Grundl · Biberach an der Riß, DE
• Alexander Pautsch · Ulm, DE

Key dates

• Filing date: Sep 10, 2015
• Grant date: Jan 10, 2017
• Expiry date: Sep 10, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to a compound of formula Iwherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.