Patent · US Active

Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent

US9574016B2 · kind B2 · utility

0Cited by

7References

8Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Ulrich Brinkmann · Weilheim, DE
Rebecca Croasdale · Antdorf, DE
Wilma Lau · Munich, DE
Guy Georges · Habach, DE
Alexander Haas · Munich, DE
Eike Hoffmann · Viernheim, DE
Silke Metz · Annaberg-Buchholz, DE
Olaf Mundigl · Weilheim, DE
Werner Scheuer · Penzberg, DE
Jan Olaf Stracke · Penzberg, DE

Key dates

Filing date	Nov 12, 2014
Grant date	Feb 21, 2017
Priority date	—
Expiry date	Nov 12, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.