Finite fully addressable nucleic acid nanostructures as nanocarriers for delivery of pharmaceuticals
US9579396B2 · kind B2 · utility
1Cited by
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26Claims
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Key dates
| Filing date | May 4, 2012 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | May 4, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2982
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest in vivo, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.