Compounds that expand hematopoietic stem cells
US9580426B2 · kind B2 · utility
4Cited by
8References
20Claims
0Family size
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Key dates
| Filing date | Apr 5, 2013 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Aug 18, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.