Patent · US Active

Benzazepine dicarboxamide compounds

US9597333B2 · kind B2 · utility

5Cited by

0References

17Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Sabine Hoves · Penzberg, DE
Lisha Wang · Basel, CH
Hongying Yun · Shanghai, CN
Weixing Zhang · Shanghai, CN
Wei Zhu · Shanghai, CN

Key dates

Filing date	Sep 28, 2016
Grant date	Mar 21, 2017
Priority date	—
Expiry date	Sep 28, 2036

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to novel benzazepine dicarboxamide compounds of the formulawherein R1 to R4 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are TLR agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.