Compositions and methods for inhibiting cytochrome P450 2D6
US9604952B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jul 29, 2014 |
| Grant date | Mar 28, 2017 |
| Priority date | — |
| Expiry date | Jul 29, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y114/14001
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of inhibiting cytochrome P450 2D6 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450 2D6. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 2D6 enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.