Patent · US Active

Antibodies with modified isoelectric points

US9605061B2 · kind B2 · utility

35Cited by

121References

7Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Bassil Dahiyat · Altadena, US
Matthew Bernett · Monrovia, US

Key dates

Filing date	Jan 27, 2014
Grant date	Mar 28, 2017
Priority date	—
Expiry date	Dec 11, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e.g. increased serum half-life in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.