Permeable glycosidase inhibitors and uses thereof
US9611275B2 · kind B2 · utility
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30Claims
0Family size
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Key dates
| Filing date | May 3, 2013 |
| Grant date | Apr 4, 2017 |
| Priority date | — |
| Expiry date | Jul 29, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds and pharmaceutical formulations comprising these compounds which are useful as O-linked N-acetylglucosaminidase (O-GlcNAcase) inhibitors, and thus may be useful for the treatment of certain disorders such as Alzheimer's disease including reducing NFTs and/or hyperphosphorylated tau. The invention is also directed to use of the compounds as O-GlcNAcase imaging agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.