Patent · US Active

Treatment of cancer with dihydropyrazino-pyrazines

US9630966B2 · kind B2 · utility

4Cited by
21References
6Claims
0Family size

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Key dates

Filing dateApr 16, 2014
Grant dateApr 25, 2017
Priority date
Expiry dateApr 16, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6886
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are methods for treating or preventing glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound to a patient having glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.