Recombinant measles virus expressing chikungunya virus polypeptides and their applications
US9655961B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 26, 2013 |
| Grant date | May 23, 2017 |
| Priority date | — |
| Expiry date | Sep 26, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to recombinant Measles virus expressing Chikungunya virus polypeptides, and concerns in particular virus like particles (VLP) that contain envelope and capsid proteins of a Chikungunya virus at their surface. These particles are recombinant infectious particles able to replicate in a host after an administration. The invention provides means, in particular nucleic acids, vectors, cells and rescue systems to produce these recombinant infectious particles. The invention also relates to the use of these recombinant infectious particles, in particular under the form of a composition, more particularly in a vaccine formulation, for the treatment or prevention of an infection by Chikungunya virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.