5-oxa-2-azabicyclo[2.2.2]OCTAN-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives

US9663530B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Giuseppe Cecere · Basel, CH
• Guido Galley · Rheinfelden (Baden), DE
• Yimin Hu · Shanghai, CN
• Roger Norcross · Olsberg, CH
• Philippe Pflieger · Schwoben, FR
• Hong Shen · Shanghai, CN

Key dates

• Filing date: Nov 21, 2016
• Grant date: May 30, 2017
• Expiry date: Nov 21, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/36
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of formula of formula I wherein X, Ar, R1, m and n are as described herein, compositions containing compounds of formula I, methods of manufacture of compounds of formula I and methods of treating psychiatric disorders with compounds of formula I.