Ghrelin mimetic polypeptide hapten immunoconjugates having improved solubility and immunogenicity and methods of use thereof
US9695222B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Feb 9, 2012 |
| Grant date | Jul 4, 2017 |
| Priority date | — |
| Expiry date | Feb 9, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/627
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunoconjugates for impeding weight gain and treating obesity in a subject are disclosed. The immunoconjugates comprise a ghrelin mimetic polypeptide hapten, a spacer moiety comprising one of more polyethylene glycol (PEG) units, and a protein carrier moiety. Immunoconjugates optionally include a conjugation moiety for conjugating the polypeptide hapten with a linker moiety or the protein carrier moiety and a linker moiety for conjugating the conjugation moiety with the protein carrier moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.