Patent · US Active

Heterodimeric proteins

US9701759B2 · kind B2 · utility

23Cited by

118References

8Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

John Desjarlais · Pasadena, US
Gregory Moore · Monrovia, US
Rumana Rashid · Temple City, US
Matthew Bernett · Monrovia, US

Key dates

Filing date	Jan 14, 2014
Grant date	Jul 11, 2017
Priority date	—
Expiry date	Aug 30, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/2896
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides heterodimeric antibodies comprising a first heavy chain comprising a first Fc domain and a single chain Fv region that binds a first antigen. The heterodimeric antibodies also comprise a second heavy chain comprising a second Fc domain, a first variable heavy chain and a first variable light chain, wherein the first and second Fc domains are different.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.