5′-end derivatives
US9725479B2 · kind B2 · utility
12Cited by
165References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Apr 22, 2011 |
| Grant date | Aug 8, 2017 |
| Priority date | — |
| Expiry date | Jun 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/344
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (1). Another aspect of the invention relates to a method of inhibiting the expression of a gene in call, the method comprising (a) contacting an oligonucleotide of the invention with the cell; and (b) maintaining the cell from step (a) for a time sufficient to obtain degradation of the mRNA of the target gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.