Anti-HER3/HER4 antibodies binding to the beta-hairpin of HER3 and the beta-hairpin of HER4

US9725511B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Birgit Bossenmaier · Hanerau-Hademarschen, DE
• Guy Georges · Habach, DE
• Michael Gerg · Munich, DE
• Gerhard Niederfellner · Oberhausen, DE
• Christian Scholz · Penzberg, DE
• Michael Schraeml · Penzberg, DE

Key dates

• Filing date: Nov 6, 2013
• Grant date: Aug 8, 2017
• Expiry date: Dec 19, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/77
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to anti-HER3/HER4 antigen binding proteins, e.g. anti-HER3/HER4 antibodies, that bind to the beta-hairpin of HER3 and the beta-hairpin of HER4, methods for selecting these antigen binding proteins, their preparation and use as medicament.