Patent · US Active

Hydroxy containing FXR (NR1H4) modulating compounds

US9751874B2 · kind B2 · utility

34Cited by

0References

12Claims

0Family size

Assignee

Gilead Sciences, Inc. · US

Inventors

Christian Gege · Ehingen (Donau), DE
Olaf Kinzel · Heidelberg, DE
Claus Kremoser · Heidelberg, DE
Aaron C. Schmitt · Hamden, US

Key dates

Filing date	Dec 16, 2015
Grant date	Sep 5, 2017
Priority date	—
Expiry date	Dec 16, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.