Patent · US Active

Chimeric antigen receptors targeting B-cell maturation antigen

US9765342B2 · kind B2 · utility

70Cited by

10References

19Claims

0Family size

Assignee

The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventor

James N. Kochenderfer · Bethesda, US

Key dates

Filing date	Mar 15, 2013
Grant date	Sep 19, 2017
Priority date	—
Expiry date	Jan 6, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/03
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.