Methods of quantitating heavy and light chain polypeptide pairs
US9771573B2 · kind B2 · utility
7Cited by
5References
36Claims
0Family size
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Key dates
| Filing date | Oct 3, 2013 |
| Grant date | Sep 26, 2017 |
| Priority date | — |
| Expiry date | Oct 3, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method of quantitatively determining the ability of individual IgG heavy chains to selectively pair with a particular IgG light chain when the heavy chains and two unique light chains are co-expressed. The method provides results with reasonable throughput and is robust and accurate. The co-expressed heavy and light chains do not need to be isolated and purified which enables more efficient screening.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.