CRISPR enzymes and systems

US9790490B2 · kind B2 · utility

Assignees

• The Broad Institute, Inc. · US
• Massachusetts Institute of Technology · US
• President and Fellows of Harvard College · US

Inventors

• Feng Zhang · Cambridge, US
• Bernd Zetsche · Cambridge, US
• Ian Slaymaker · Cambridge, US
• Jonathan Gootenberg · Cambridge, US
• Omar Abudayyeh · Cambridge, US

Key dates

• Filing date: Dec 18, 2015
• Grant date: Oct 17, 2017
• Expiry date: Dec 18, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.