Patent · US Active

2-phenylimidazo[1,2-a]pyrimidines as imaging agents

US9801961B2 · kind B2 · utility

0Cited by

1References

6Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Luca Gobbi · Muttenz, CH
Henner Knust · Rheinfelden (Baden), DE
Matthias Koerner · Antdorf, DE
Dieter Muri · Basel, CH

Key dates

Filing date	Nov 19, 2015
Grant date	Oct 31, 2017
Priority date	—
Expiry date	Jan 22, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of general formulawherein R is hydrogen, halogen, lower alkyl substituted by halogen or lower alkoxy; The compounds are suitable as imaging tool, which will improve diagnosis by identifying potential patients with excess of tau aggregates in the brain, which may be likely to develop Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.