Antibody formulations

US9821065B2 · kind B2 · utility

Assignee

• Genentech, Inc. · US

Inventors

• Yatin R. Gokarn · San Diego, US
• Isidro E. ZARRAGA · South San Francisco, US
• Jonathan ZARZAR · South San Francisco, US
• Thomas Patapoff · South San Francisco, US
• Christine Wurth · Basel, CH

Key dates

• Filing date: Mar 13, 2014
• Grant date: Nov 21, 2017
• Expiry date: Apr 30, 2034

Classification

• Technology area (CPC —): General

Abstract

The invention provides stable aqueous pharmaceutical formulations comprising a therapeutic antibody, trehalose, a buffer, and optional surfactant, and having a pH in the range of about 5.5 to about 7.0. The invention also provides methods for making such formulations and methods of using such formulations.