HER1 antigen binding proteins binding to the beta-hairpin of HER1

US9840565B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Birgit Bossenmaier · Hanerau-Hademarschen, DE
• Michael Gerg · Munich, DE
• Gerhard Niederfellner · Oberhausen, DE
• Carmen Peess · Tutzing, DE
• Michael Schraeml · Penzberg, DE

Key dates

• Filing date: May 12, 2015
• Grant date: Dec 12, 2017
• Expiry date: May 12, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/77
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to anti-HER1 antigen binding proteins, e.g. anti-HER1 antibodies, that bind to the beta-hairpin of HER1, methods for selecting these antigen binding proteins, their preparation and use as medicament.