Patent · US Active

Thiazoles as modulators of RORγt

US9861618B2 · kind B2 · utility

0Cited by

2References

8Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Steven Goldberg · Encinitas, US
Christoph Steeneck · Dossenheim, DE
Christian Gege · Ehingen (Donau), DE
Olaf Kinzel · Heidelberg, DE
Gerald Kleymann · Bad Salzuflen, DE
Thomas Hoffmann · Santa Cruz, US

Key dates

Filing date	Oct 30, 2015
Grant date	Jan 9, 2018
Priority date	—
Expiry date	Oct 30, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention comprises compounds of Formula Iwherein:R1, R2, R3, R4, R5, R7, R8, andare defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.