Method for determining cell state and autoanalyzer using said method
US9862921B2 · kind B2 · utility
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Key dates
| Filing date | Jun 17, 2014 |
| Grant date | Jan 9, 2018 |
| Priority date | — |
| Expiry date | Jun 18, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6812
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is provided a method for noninvasively evaluating the cell state (proliferation, multi-layering, and differentiation) of a cell sheet as a mimic tissue at the time of culturing the cell sheet. The method is characterized in that an analysis of an amino acid is conducted with the use of the culture supernatant of a cell sheet to monitor a change in the concentration of any amino acid selected from a group of 5-species of amino acids (Ile, Val, Ser, Leu, and Ala), thereby making a determination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.