Electron consuming ethanol production pathway to displace glycerol formation in S. cerevisiae
US9868965B2 · kind B2 · utility
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| Filing date | Nov 20, 2013 |
| Grant date | Jan 16, 2018 |
| Priority date | — |
| Expiry date | Nov 20, 2033 |
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- Technology area (CPC —)General
Abstract
The present invention provides for a mechanism to completely replace the electron accepting function of glycerol formation with an alternative pathway to ethanol formation, thereby reducing glycerol production and increasing ethanol production. In some embodiments, the invention provides for a recombinant microorganism comprising a down-regulation in one or more native enzymes in the glycerol-production pathway. In some embodiments, the invention provides for a recombinant microorganism comprising an up-regulation in one or more enzymes in the ethanol-production pathway.
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