Substituted spirocycles

US9879026B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Viktor Vintonyak · Warthausen, DE
• Matthias Grauert · Ingelheim am Rhein, DE
• Marc Grundl · Biberach an der Riß, DE
• Alexander Pautsch · Ulm, DE

Key dates

• Filing date: Nov 29, 2016
• Grant date: Jan 30, 2018
• Expiry date: Nov 29, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to a compound of formula Iwherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.