Chemical regeneration method of oxidized coenzyme NAD (P)+
US9884888B2 · kind B2 · utility
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Key dates
| Filing date | May 19, 2016 |
| Grant date | Feb 6, 2018 |
| Priority date | — |
| Expiry date | May 19, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/584
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase.
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