Trivalent, bispecific antibodies

US9890204B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Ulrich Brinkmann · Weilheim, DE
• Rebecca Croasdale · Antdorf, DE
• Eike Hoffmann · Viernheim, DE
• Christian Klein · Iffeldorf, DE
• Ekkehard Moessner · Kreuzlingen, CH
• Juergen Michael Schanzer · Traunstein, DE
• Claudio Sustmann · Munich, DE
• Pablo Umana · Wollerau, CH

Key dates

• Filing date: Aug 7, 2012
• Grant date: Feb 13, 2018
• Expiry date: Aug 7, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to trivalent, bispecific antibodies, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.