Patent · US Active

2,2,2-trifluoroethyl-thiadiazines

US9896438B2 · kind B2 · utility

0Cited by

0References

20Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Lilli Anselm · Binzen, DE
Bjoern Bartels · Schopfheim, DE
Cosimo Dolente · Allschwil, CH
Wolfgang Guba · Memmingen, DE
Haap Wolfgang · Soest, DE
Jens-Uwe Peters · Weil am Rhein, DE
Thomas Woltering · Glückstadt, DE
Ulrike Obst Sander · Sursee, CH
Mark Rogers-Evans · Bottmingen, CH

Key dates

Filing date	Aug 12, 2015
Grant date	Feb 20, 2018
Priority date	—
Expiry date	Aug 12, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a compound of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.