Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

US9931334B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• Patricia Hurter · Harvard, US
• William Rowe · Medford, US
• Christopher R. Young · Waltham, US
• Adriana Costache · Cambridge, US
• Patrick R. Connelly · Harvard, US
• Mariusz Krawiec · Marlborough, US
• Yuchuan Gong · Waukegan, US
• Yushi Feng · Zionsville, US
• Martin Trudeau · Shannon, US

Key dates

• Filing date: May 2, 2017
• Grant date: Apr 3, 2018
• Expiry date: May 2, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.