Patent · US Active

Antidiabetic tricyclic compounds

US9932311B2 · kind B2 · utility

4Cited by
2References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 30, 2014
Grant dateApr 3, 2018
Priority date
Expiry dateSep 30, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.